Abstract
Abstract
Technological advances in electrically active implantable devices have increased the complexity of hardware design. In particular, the increasing number of stimulation and recording channels requires innovative approaches for connectors that interface electrodes with the implant circuitry. Objective. This work aims to provide a common theoretical ground for implantable connector development with a focus on neural applications. Approach. Aspects and experiences from several disciplines are compiled from an engineering perspective to discuss the state of the art of connector solutions. Whenever available, we also present general design guidelines. Main results. Degradation mechanisms, material stability and design rules in terms of biocompatibility and biostability are introduced. Considering contact physics, we address the design and characterization of the contact zone and review contaminants, wear and contact degradation. For high-channel counts and body-like environments, insulation can be even more crucial than the electrical connection itself. Therefore, we also introduce the requirements for electrical insulation to prevent signal loss and distortion and discuss its impact on the practical implementation. Significance. A final review is dedicated to the state of the art connector concepts, their mechanical setup, electrical performance and the interface to other implant components. We conclude with an outlook for possible approaches for the future generations of implants.
Funder
Bundesministerium für Bildung und Forschung
Deutsche Forschungsgemeinschaft
Subject
Cellular and Molecular Neuroscience,Biomedical Engineering
Reference166 articles.
1. Lessons from the first patient with an implanted pacemaker: 1958–2001;Larsson;Pacing. Clin. Electrophysiol.,2003
2. Brain–computer interfaces: an overview of the hardware to record neural signals from the cortex;Stieglitz,2009
3. Upper and lower extremity motor neuroprostheses;Kilgore,2004
4. Cochlear implants;Seligman,2004
5. Can vision be restored by electrical stimulation?;Margalit,2004
Cited by
29 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献