Live-cell imaging reveals divergent intracellular dynamics of polyglutamine disease proteins and supports a sequestration model of pathogenesis
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference39 articles.
1. Expansion explosion: new clues to the pathogenesis of repeat expansion neurodegenerative diseases
2. Chaperone suppression of aggregation and altered subcellular proteasome localization imply protein misfolding in SCA1
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4. Polyglutamine-Expanded Androgen Receptors Form Aggregates That Sequester Heat Shock Proteins, Proteasome Components and SRC-1, and Are Suppressed by the HDJ-2 Chaperone
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