Cooling inflammation while potentiating immune checkpoint inhibition: Enhancing the benefit–risk ratio of immuno-oncology therapy
Author:
Affiliation:
1. Department of Medicine, Division of Hematology, Oncology, and Transplantation and Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455
2. Masonic Cancer Center, Minneapolis, MN 55455
Funder
DOD | USA | MEDCOM | CDMRP | DOD Peer Reviewed Cancer Research Program
HHS | NIH | NCI | Center for Cancer Research
Publisher
Proceedings of the National Academy of Sciences
Link
https://pnas.org/doi/pdf/10.1073/pnas.2400431121
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1. Enhancing cancer immunotherapy via inhibition of soluble epoxide hydrolase
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4. Epoxyeicosanoids stimulate multiorgan metastasis and tumor dormancy escape in mice
5. CYP3A4 Mediates Growth of Estrogen Receptor-positive Breast Cancer Cells in Part by Inducing Nuclear Translocation of Phospho-Stat3 through Biosynthesis of (±)-14,15-Epoxyeicosatrienoic Acid (EET)
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