An essential amino acid residue in the protein translocation channel revealed by targeted random mutagenesis of SecY
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference24 articles.
1. PROTEIN TRANSPORT ACROSS THE EUKARYOTIC ENDOPLASMIC RETICULUM AND BACTERIAL INNER MEMBRANES
2. The Translocon: A Dynamic Gateway at the ER Membrane
3. The major pathways of protein translocation across membranes
4. The SecA and SecY subunits of translocase are the nearest neighbors of a translocating preprotein, shielding it from phospholipids.
5. The ATPase activity of secA is regulated by acidic phospholipids, secY, and the leader and mature domains of precursor proteins
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