Danish dementia mice suggest that loss of function and not the amyloid cascade causes synaptic plasticity and memory deficits
Author:
Publisher
Proceedings of the National Academy of Sciences
Subject
Multidisciplinary
Reference32 articles.
1. A decamer duplication in the 3' region of the BRI gene originates an amyloid peptide that is associated with dementia in a Danish kindred
2. Axonal transport of British and Danish amyloid peptides via secretory vesicles
3. Cerebral Amyloid Angiopathy and Parenchymal Amyloid Deposition in Transgenic Mice Expressing the Danish Mutant Form of Human BRI2
4. Modeling familial Danish dementia in mice supports the concept of the amyloid hypothesis of Alzheimer's disease
5. The presenilin hypothesis of Alzheimer's disease: Evidence for a loss-of-function pathogenic mechanism
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