1. expression and phosphorylatin of regula- Hedley et al. (29). The polymerized form of
2. tory proteins. The presence of metallo- metailothionein in the nucleus of forma
3. thionein in the cell nucleus can effectively lin-fixed tissues cannot leach out and
4. donate zinc to several enzymes or chelate therfore intact nuclei containing metalloth
5. zinc from transcription factors such as zinc ionein can be isolated. Thus the physiolog