Protective Role of Interleukin-10 in Ozone-Induced Pulmonary Inflammation

Author:

Backus Gillian S.1,Howden Reuben2,Fostel Jennifer1,Bauer Alison K.3,Cho Hye-Youn1,Marzec Jacqui1,Peden David B.4,Kleeberger Steven R.1

Affiliation:

1. National Institute of Environmental Health Sciences, Laboratory of Respiratory Biology, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, North Carolina, USA;

2. University of North Carolina–Charlotte, Department of Kinesiology, Charlotte, North Carolina, USA;

3. Michigan State University, Department of Pathobiology and Diagnostic Investigation, Center for Integrative Toxicology, East Lansing, Michigan, USA;

4. Center for Environmental Medicine, Asthma and Lung Biology, Department of Pediatrics, and Division of Immunology and Infectious Disease, University of North Carolina–Chapel Hill School of Medicine, Chapel Hill, North Carolina, USA

Publisher

Environmental Health Perspectives

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Reference48 articles.

1. Mechanism of IL-10-Induced T Cell Inactivation in Allergic Inflammation and Normal Response to Allergens

2. American Physiological Society. 2002. Appendix C. Guiding Principles for Research Involving Animals and Human Beings. Recommendations From The Revised Declaration of Helsinki by the World Medical Association Regarding Human Subjects Available: http://www.the-aps.org/about/opguide/appendix.htm#guiding (accessed 21 September 2010).

3. Identification of novel susceptibility genes in ozone-induced inflammation in mice;Bauer AK;Eur Respir J,2009

4. Involvement of Suppressor of Cytokine Signaling-3 as a Mediator of the Inhibitory Effects of IL-10 on Lipopolysaccharide-Induced Macrophage Activation

5. Amelioration of Ozone-Induced Lung Injury by Anti-Tumor Necrosis Factor-alpha

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