Blood groups and SARS-CoV-2 infection in Pinar del Río medical students

Author:

Miló-Valdés Carlos AlfredoORCID,Lugo Hernández AlbertoORCID,Pino Falcón AnthuanetORCID,García García MayelínORCID,Vitón-Castillo Adrián AlejandroORCID,Orraca-Castillo OdalysORCID

Abstract

Introduction: the influence of ABO and Rh blood type on susceptibility to infections by different agents has been studied and verified. Increasing evidence suggests that the ABO blood group plays a role in the immunopathogenesis of SARS-CoV-2 infection. Objective: determine the association between blood group and SARS-CoV-2 infection in second-year medical students from Pinar del Río. Methods: an analytical, cross-sectional, retrospective study was carried out; in 402 second-year medical students from Pinar del Río, between February and May 2022. The blood group of the participants was determined using the immunohemagglutination technique. Results: groups A and O predominated in the sample with the same number of 173 individuals (43,03 %). 85,82 % were Rh positive. 35,82 % of the subjects had Covid-19. 45,14 % of the individuals who had Covid-19 were from group O and 38,19 % from group A; 80,56 % were Rh positive. Similarly, 34,72 % of the subjects who had Covid-19 were O+. In the association analyses, no statistically significant relationships were found in any of the comparison designs. Conclusions: the role of ABO blood group in SARS-CoV-2 infectivity and COVID-19 disease severity requires additional studies. The hypothesis that blood group was an influential factor in SARS-CoV-2 infection could not be proven or refuted.

Publisher

Salud, Ciencia y Tecnologia

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