Author:
Jaspars Marcel,De Pascale Donatella,Andersen Jeanette H.,Reyes Fernando,Crawford Alexander D.,Ianora Adrianna
Abstract
Marine organisms possess the capacity to produce a variety of unique and biologically potent natural products for treating human diseases, many of which are currently commercially available or are in advanced clinical trials. Here we provide a short review on progress in the field and discuss a case study of an EU-funded project, PharmaSea, which aims to discover novel products for the treatment of infections, inflammation and neurodegenerative diseases. Research in this sector is opening new doors for harnessing the potential of marine natural products with pharmaceutical properties.
Publisher
Cambridge University Press (CUP)
Reference34 articles.
1. Drug development: the journey of a medicine from lab to shelf;Torjesen;Pharmaceutical Journal,2015
2. Clinical impact of trabectedin (ecteinascidin-743) in advanced/metastatic soft tissue sarcoma
3. Eribulin (Halaven): a new, effective treatment for women with heavily pretreated metastatic breast cancer;Menis;Breast Cancer: Targets Therapy,2011
4. Marine Pharmacology in 2009–2011: Marine Compounds with Antibacterial, Antidiabetic, Antifungal, Anti-Inflammatory, Antiprotozoal, Antituberculosis, and Antiviral Activities; Affecting the Immune and Nervous Systems, and other Miscellaneous Mechanisms of Action
5. The odyssey of marine pharmaceuticals: a current pipeline perspective
Cited by
134 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献