Author:
Ostlind D. A.,Nartowicz M. A.,Mickle W. G.
Abstract
ABSTRACTIvermectin was evaluated against natural and artificial pinworm (Syphacia) infections in mice. Ivermectin given in the diet for 6 days at 0·0005% was 99% effective against both immature and adult worms. A diet level of 0·0004% reduced immature and mature pinworm by 99 and 75%, respectively but 0·0001% was inactive. One oral dose of 2·0mg/kg was 100 and 97% effective against gravid females and immature worms, respectively. A dose of 1·0 mg/kg was 96 and 66% effective against the same parasitic stages. A similar effect was observed against adult male worms where 94 and 86% were removed by one oral dose of ivermectin at 2·0 and 1·0 mg/kg, respectively.
Publisher
Cambridge University Press (CUP)
Subject
Animal Science and Zoology,General Medicine,Parasitology
Reference10 articles.
1. Blair L. S. & Campbell W. C. (1978) Efficacy of avermectins against gastrointestinal helminths in dogs. Program Abstract 53rd Annual Meeting, American Society of Parasitologists, Chicago, Nov. 5–10, 1978, 1978, No. 148.
2. Anthelmintic 2-(5-nitro-2-thienyl)-4-(substituted amino)quinazolines
3. Efficacy of thiabendazole, levamisole hydrochloride and the major natural avermectins against Trichostrongylus colubriformis in the gerbil (Meriones unguiculatus);Ostlind;Research in Veterinary Science,1981
4. Life cycle studies on the nematode Syphacia obvelata;Chan;American Journal of Hygiene,1952
5. The antiparasitic activity of ivermectin in horses
Cited by
14 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献