Conversion by corynephages and its role in the natural history of diphtheria

Author:

Groman N. B.

Abstract

SummaryThe conversion of non-toxinogenicCorynebacterium diphtheriaeto toxinogeny has been reviewed. The biology of converting phage and the relationship of converting phages to nonconverting phages are summarized. The significance of these findings to the natural history and evolution of diphtheria is assessed.

Publisher

Cambridge University Press (CUP)

Subject

Public Health, Environmental and Occupational Health,Immunology

Reference53 articles.

1. Isolation and characterization of tox mutants of corynebacteriophage beta;Laird;Journal of Virology,1976

2. Extrachromosomal elements as possible agents of adaptation and development;Reanney;Bacteriological Review,1976

3. Evidence for the induced nature of the change from nontoxigenicity to toxigenicity in Corynebacterium diphtheriae as a result of exposure to specific bacteriophage;Groman;Journal of Bacteriology,1953

4. Mutation in the structural gene for diphtheria toxin carried by temperate phage β;Uchida;Nature, London,1971

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