Differential regulation ofPandhobomobile elements by two laboratory strains ofDrosophila melanogaster

Abstract

SummaryAnalysis of the transposition behaviour of thePandhoboelements borne by the31·1/CyL4MRF (P), 23·5Δ/CyL4MRF (hobo)and23·5*/Cy MRF (hobo)strains in the progeny of dysgenic crosses with two ME laboratory strains (Berlin-k and dp b en bw) at 25 °C revealed that: (a) the two ME laboratory strains affect differently the transposition rates ofPandhoboelements. More precisely,Pelement transposition is higher in heterozygotes withdp b en bwthan in those withBerlin-k. In contrast, the transposition rate ofhoboelements is higher inBerlin-kthan indp b cn bwheterozygotes. (b) LikeP, hobohas the potential to transpose at high frequencies and to nonhomologous chromosomes, (c) The dysgenically inactivehoboelements of the3·11 MRFstrain transpose more frequently than the dysgenically activehoboelements of the23·5 MRFstrains in certain crosses, (d) There are insertion hot spots forPandhoboelements. For thePelements there are enough data to suggest that the insertion hot spots are different in the two EM strains. The data are discussed on the basis of the involvement of putative host factors in transposition regulation of thePandhoboelements.