Author:
Cattanach B. M.,Williams C. E.
Abstract
SUMMARYX-linked modification of the heterozygous phenotypes of X-linked genes has been detected in the X chromosomes of several inbred strains of mice. The effect is similar to that of the alternative ‘states’ or alleles, of theX chromosome controlling element, Xce, identified in T(1; X)Ct X chromosomes. Tests on two such differing X chromosomes have indicated that the phenotypic modification results either from non-random inactivation of the two X chromosomes or from selection operating on the two cell populations differentiated by X-inactivation. The data provide evidence of non-random X chromosome activity in the somatic cells of the female mouse.
Subject
Genetics,General Medicine
Reference23 articles.
1. Genes and genotypes affecting the teeth of the mouse;Gruneberg;Journal of Embryology and Experimental Morphology,1965
2. A chemically-induced variegated-type position effect in the mouse;Cattanach;Zeitscherift für Vererbungslehre,1961
3. Controlling elements in the mouseX-chromosome III. Influence upon both parts of anXdivided by rearrangement
4. The inactive-X hypothesis and position effects in the mouse;Cattanach;Genetics,1963
5. A maternal effect on vibrissa score due to the Tabby gene;Kindred;Australian Journal of Biological Science,1961
Cited by
89 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献