Author:
Wernovsky Gil,Chrisant Maryanne R. K.
Abstract
As recently as 35 years ago, children born with a functionally single ventricle were destined to a lifetime of multiple palliative operations, and disrupted growth and development. Physical signs of their cardiac disease were evidenced by chronic hypoxemia, polycythemia, clubbing, small stature, and severely reduced exercise ability. A normal lifestyle, with typical landmarks such as uninterrupted adolescence and potential childbearing, was unlikely. The successful application of right heart bypass by Fontan and Kreutzer in the early 1970s heralded an era of multiple medical and surgical breakthroughs that have systematically improved the quality of life and long-term outlook for these children.
Publisher
Cambridge University Press (CUP)
Subject
Cardiology and Cardiovascular Medicine,General Medicine,Pediatrics, Perinatology, and Child Health
Reference104 articles.
1. Mahle WT , Clancy RR , Moss E , Gerdes M , Jobes DR , Wernovsky G . Neurodevelopmental outcome and lifestyle assessment in school-age and adolescent children with hypoplastic left heart syndrome. Pediatrics 2000; 105: 1082–1089.
2. Truwit CL , Denaro CP , Lake JR , et al. MR imaging of reversible cyclosporine A induced neurotoxicity. Am J Nuclear Radiol 1991; 12: 651–656.
3. Williams DL , Gelijns AC , Moskowitz AJ , et al. Hypoplastic left heart syndrome: valuing the survival. J Thorac Cardiovasc 2000; 119: 720–731.
4. Mulla NF , Johnston JK , Vander Dussen LK , et al. Late rejection is a predictor of transplant coronary artery disease in children. J Am Coll Cardiol 2001; 37: 243–250.
5. Hsu DT , Garofano RP , Douglas JM , et al. Exercise performance after pediatric heart transplantation. Circ 1993; 88 (Suppl. II): II-236–II-243.
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