Long-term follow-up after staged reconstruction or transplantation for patients with functionally univentricular heart

Author:

Wernovsky Gil,Chrisant Maryanne R. K.

Abstract

As recently as 35 years ago, children born with a functionally single ventricle were destined to a lifetime of multiple palliative operations, and disrupted growth and development. Physical signs of their cardiac disease were evidenced by chronic hypoxemia, polycythemia, clubbing, small stature, and severely reduced exercise ability. A normal lifestyle, with typical landmarks such as uninterrupted adolescence and potential childbearing, was unlikely. The successful application of right heart bypass by Fontan and Kreutzer in the early 1970s heralded an era of multiple medical and surgical breakthroughs that have systematically improved the quality of life and long-term outlook for these children.

Publisher

Cambridge University Press (CUP)

Subject

Cardiology and Cardiovascular Medicine,General Medicine,Pediatrics, Perinatology, and Child Health

Cited by 8 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Hypoplasia of the Left Heart;Paediatric Cardiology;2010

2. The Paradigm Shift Toward Surgical Intervention for Neonates With Hypoplastic Left Heart Syndrome;Archives of Pediatrics & Adolescent Medicine;2008-09-01

3. What is the impact of antenatal diagnosis on long-term outlook?;Pediatric Radiology;2008-05-10

4. Decreased Exercise Performance with Age in Children with Hypoplastic Left Heart Syndrome;The Journal of Pediatrics;2008-04

5. Hypoplastic left heart syndrome;Orphanet Journal of Rare Diseases;2007-05-11

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