Author:
SIDDIQUE A. K.,NAIR G. B.,ALAM M.,SACK D. A.,HUQ A.,NIZAM A.,LONGINI I. M.,QADRI F.,FARUQUE S. M.,COLWELL R. R.,AHMED S.,IQBAL A.,BHUIYAN N. A.,SACK R. B.
Abstract
SUMMARYDuring epidemics of cholera in two rural sites (Bakerganj and Mathbaria), a much higher proportion of patients came for treatment with severe dehydration than was seen in previous years. V. cholerae O1 isolated from these patients was found to be El Tor in its phenotype, but its cholera toxin (CT) was determined to be that of classical biotype. Whether the observed higher proportion of severe dehydration produced by the El Tor biotype was due to a shift from El Tor to classical CT or due to other factors is not clear. However, if cholera due to strains with increased severity spread to other areas where treatment facilities are limited, there are likely to be many more cholera deaths.
Publisher
Cambridge University Press (CUP)
Subject
Infectious Diseases,Epidemiology
Reference23 articles.
1. Why Cholera Still Takes Lives in Rural Bangladesh
2. Monoclonal antibodies to Escherichia coli heat-labile enterotoxins: neutralising activity and differentiation of human and porcine LTs and cholera toxin;Svennerholm;Medical Biology,1986
3. Emergence of a new epidemic strain of Vibrio cholerae in Bangladesh: an epidemiological study;Siddique;Tropical and Geographical Medicine,1994
4. New Variants of
Vibrio cholerae
O1 Biotype El Tor with Attributes of the Classical Biotype from Hospitalized Patients with Acute Diarrhea in Bangladesh
Cited by
108 articles.
订阅此论文施引文献
订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献