A Genetic Study of Erythrocyte Arginine-tRNA Synthetase Activity in Man-Reference-Cited by-同舟云学术

A Genetic Study of Erythrocyte Arginine-tRNA Synthetase Activity in Man

Published:1977-01 Issue:1 Volume:26 Page:21-27
ISSN:1120-9623
Container-title:Acta geneticae medicae et gemellologiae
language:en
Short-container-title:Acta genet. med. gemellol.

Author:

McCune Sylvia A.,Yu P. L.,Nance Walter E.

Abstract

To search for evidence of genetic variation among the aminoacyl-tRNA synthetases, a semi-automated assay procedure employing a Technicon Auto Analyzer was used to measure erythrocyte arginine-tRNA synthetase activity in samples obtained from normal human twins of various ages. Variation in enzyme activity within the older DZ twins was five times that of the MZ twins suggesting the existence of genetically determined variation in enzyme activity. Higher enzyme activity was observed in newborn DZ unlike-sexed twins than in like-sexed twins of either zygosity. Possible explanations for this observation are discussed.

Publisher

Cambridge University Press (CUP)

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