Maternal and Fetal Outcome among Women having Pre Eclampsia with Hyperuricemia

Abstract

Objective: To find out the frequency of some common maternal and fetal outcomes among women having pre eclampsia with hyperuricemia. Study design: Cross sectional study. Place and duration of study: Department of Obstetrics and Gynaecology, Hayatabad Medical Complex, Peshawar from April 2019 to Oct 2019. Patients and methods: A total of 161 women with singleton pregnancy irrespective of gravity and party, in age group ranging from 20-35 years having pre eclampsia with hyperuricemia were included in consective manner. All patients signed informed written consent for study and its outcome. Detailed history taking and examination were performed and standard lab investigations were sent. All patients were followed up till 40th day of delivery for maternal (caesarean section, eclampsia and maternal death) and fetal outcome [intrauterine fetal death, (small for gestational age) SGA and APGAR score]. Data was analyzed using SPSS version 20. Results: Maternal complications in patients of pre eclampsia with hyperuricemia were eclampsia 15.5%, caesarean section 18% and death 19.3%. Fetal complications included SGA 11.8%, intrauterine death 16.8% and APGAR score at 5 minutes 24.2%. The mean age and standard deviation of sample were 28.4 + 4.8 years, mean gravidity (2.7±1.1), mean parity (2.4±0.9) and mean BMI (24.37±2.4 kg/m2). Conclusion: Hyperuricemia in pre-eclampsia is a poor prognostic factor with increased maternal and fetal deaths, worsening of pre eclampsia to eclampsia and low APGAR scores of fetus. Key words: Pre eclampsia, hyperuricemia, maternal death, caesarean section, small for gestational age, APGAR score