Study of the role of an infectious factor in the development of stroke in children. Results of a 5-year retrospective analysis

Abstract

Objective: Determine the role of infectious diseases in the development of strokes in children and to identify risk groups for its progression.Materials and Methods: A retrospective analysis of 660 case histories of children aged 1 months to 1 8 years old, hospitalized in Morozov Children's City Clinical Hospital with stroke in the period from 201 6 to July 2020 was carried out.Results. An infectious disease or fever 4 weeks before stroke is diagnosed in 78 (1 2%) cases. Infections more often act as a stroke trigger in children under 7 years old (28% in children under one year old). The incidence of strokes against a background of a bacterial infection is higher than against a background of a viral infection (47% versus 35%). Among bacterial infections, meningitis (35%), otitis media (24%), pneumonia (1 8%) prevailed. With a viral infection, viruses of Herpes are more common (44%), as well as respiratory viruses (37%). Two cases of cerebrovascular accident were revealed in children who have undergone a new coro-navirus infection SARS-CoV-2 (7%). Among the types of stroke, with bacterial infection, sinus thrombosis was more common (50%), among viral infection, the most common was ischemic stroke (60%). The presence of an additional risk factor was revealed in 72%, most often these were prothrombotic conditions (35%).