1. Russell WMS, Burch RL (1959) The Principles of Humane Experimental Technique.
2. The three Rs: the way forward;J Zurlo;Environ Health Perspect,1996
3. The Three Rs Declaration of Bologna, Adopted by the third World Congress on Alternative and Animal Use in the Life Sciences, Bologna, Italy, on 31 August 1999;Altern Lab Anim,2009
4. European Union (2010) Directive 2010/63/EU of the Eurpean Parliament and of the Council of 22 September 2010 on the protection of animals used for scientific purposes. OJEU L 276/33.
5. The Brazilian legal framework on the scientific use of animals;AT Filipecki;Ilar J,2011