Recurrence of pulmonary tuberculosis in India: Findings from the 2019–2021 nationwide community-based TB prevalence survey

Author:

Giridharan PrathikshaORCID,Selvaraju Sriram,Rao Raghuram,Rade Kiran,Thiruvengadam Kannan,Asthana SmitaORCID,Balachandar Rakesh,Dipak Bangar Sampada,Bansal Avi Kumar,Bhat JyothiORCID,Chakraborty Debjit,Chopra Vishal,Das Dasarathi,Dutta Shanta,Rekha Devi Kangjam,Kumar Sunil,Laxmaiah Avula,Madhukar MajorORCID,Mahapatra Amarendra,Mohanty Suman Sundar,Rangaraju Chethana,Turuk Jyotirmayee,Zaman KamranORCID,Krishnan Rajendran,Shanmugam Sivakumar,Kumar Nishant,Panduranga Joshi Rajendra,Narasimhaiah Somashekar,Chandrasekaran Padmapriyadarsini,Gangakhedkar Raman R.,Bhargava Balram

Abstract

Recurrent Tuberculosis patients contribute to a significant proportion of TB burden in India. A nationwide survey was conducted during 2019–2021 across India among adults to estimate the prevalence of TB. A total of 322480 individuals were screened and 1402 were having TB. Of this, 381 (27.1%) had recurrent TB. The crude prevalence (95% CI) of recurrent TB was 118 (107–131) per 100,000 population. The median duration between episodes of TB was 24 months. The proportion of drug resistant TB was 11.3% and 3.6% in the recurrent group and new TB patients respectively. Higher prevalence of recurrent TB was observed in elderly, males, malnourished, known diabetics, smokers, and alcohol users. (p<0.001). To prevent TB recurrence, all treated tuberculosis patients must be followed at least for 24 months, with screening for Chest X-ray, liquid culture every 6 months, smoking cessation, alcohol cessation, nutritional interventions and good diabetic management.

Funder

Ministry of Health and Family Welfare, Government of India

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

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