MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT

Author:

Keravnou Anna,Ioannides Marios,Loizides Charalambos,Tsangaras Kyriakos,Achilleos Achilleas,Mina Petros,Kypri Elena,Hadjidaniel Michael D.,Neofytou MariaORCID,Kyriacou Skevi,Sismani Carolina,Koumbaris George,Patsalis Philippos C.ORCID

Funder

ERC Advanced Grant

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference43 articles.

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3. Noninvasive Prenatal Test by Cell-Free Fetal DNA in Maternal Plasma;M Motavaf;Current Progress and Prospective Clinical Applications,2014

4. mRNA of placental origin is readily detectable in maternal plasma;EKO Ng;Proc Natl Acad Sci U S A,2003

5. Post-genomics studies and their application to non-invasive prenatal diagnosis;ND Avent;Semin Fetal Neonatal Med,2008

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