A Novel Formulation of Tigecycline Has Enhanced Stability and Sustained Antibacterial and Antileukemic Activity

Author:

Jitkova Yulia,Gronda Marcela,Hurren Rose,Wang Xiaoming,Goard Carolyn A.,Jhas Bozhena,Schimmer Aaron D.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference25 articles.

1. Tigecycline;R Wenzel;Nat Rev Drug Discov,2005

2. Synthesis and structure-activity relationship of novel glycylcycline derivatives leading to the discovery of GAR-936;PE Sum;Bioorg Med Chem Lett,1999

3. In vitro and in vivo antibacterial activities of a novel glycylcycline, the 9-t-butylglycylamido derivative of minocycline (GAR-936);PJ Petersen;Antimicrob Agents Chemother,1999

4. Wyeth Pharmaceuticals Inc. 2012) Tygacil: Full Prescribing Information. Available online: http://labeling.pfizer.com/showlabeling.aspx?id=491 (Accessed 8 July 2013).

5. Pharmacokinetic and pharmacodynamic evaluation of tigecycline;H Giamarellou;Expert Opin Drug Metab Toxicol,2011

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