Spinocerebellar ataxia type 11-associated alleles of Ttbk2 dominantly interfere with ciliogenesis and cilium stability

Author:

Bowie Emily,Norris Ryan,Anderson Kathryn V.ORCID,Goetz Sarah C.ORCID

Funder

Eunice Kennedy Shriver National Institute of Child Health and Human Development

National Ataxia Foundation

National Institute of Neurological Disorders and Stroke

Publisher

Public Library of Science (PLoS)

Subject

Cancer Research,Genetics (clinical),Genetics,Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference39 articles.

1. The primary cilium: a signalling centre during vertebrate development;SC Goetz;Nat Rev Genet. Nature Publishing Group,2010

2. Cilia: traffic directors along the road of cortical development;C Métin;Neuroscientist. SAGE Publications,2014

3. Hedgehog trafficking, cilia and brain functions;M Ruat;Differentiation,2012

4. The spinocerebellar ataxia-associated gene Tau tubulin kinase 2 controls the initiation of ciliogenesis;SC Goetz;Cell. Elsevier Ltd,2012

5. Tau-tubulin kinase phosphorylates tau at Ser-208 and Ser-210, sites found in paired helical filament-tau;K Tomizawa;FEBS Lett,2001

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