Hydroxychloroquine partially prevents endothelial dysfunction induced by anti-beta-2-GPI antibodies in an in vivo mouse model of antiphospholipid syndrome

Author:

Urbanski GeoffreyORCID,Caillon Antoine,Poli Caroline,Kauffenstein Gilles,Begorre Marc-Antoine,Loufrani Laurent,Henrion Daniel,Belizna Cristina

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference49 articles.

1. International consensus statement on an update of the classification criteria for definite antiphospholipid syndrome (APS);S Miyakis;J Thromb Haemost JTH,2006

2. Anti-phospholipid antibodies are directed against a complex antigen that includes a lipid-binding inhibitor of coagulation: beta 2-glycoprotein I (apolipoprotein H);HP McNeil;Proc Natl Acad Sci U S A,1990

3. Molecular definition of human beta 2-glycoprotein I (beta 2-GPI) by cDNA cloning and inter-species differences of beta 2-GPI in alternation of anticardiolipin binding;E Matsuura;Int Immunol,1991

4. The anti-beta2-glycoprotein I activity in human anti-phospholipid syndrome sera is due to monoreactive low-affinity autoantibodies directed to epitopes located on native beta2-glycoprotein I and preserved during species’ evolution;A Tincani;J Immunol Baltim Md,1996

5. Do some antiphospholipid antibodies target endothelial cells?;M Dueymes;Ann Med Interne (Paris),1996

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