T vector velocity: A new ECG biomarker for identifying drug effects on cardiac ventricular repolarization

Author:

Bystricky WernerORCID,Maier Christoph,Gintant Gary,Bergau DennisORCID,Kamradt Kent,Welsh PatrickORCID,Carter DavidORCID

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference31 articles.

1. ICH. The clinical evaluation of qt/qtc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs; 2005. http://www.ich.org/fileadmin/Public_Web_Site/ICH_Products/Guidelines/Efficacy/E14/E14_Guideline.pdf.

2. Measurement and regulation of cardiac ventricular repolarization: from the QT interval to repolarization morphology;JP Couderc;Philosophical Transactions Series A, Mathematical, Physical, and Engineering Sciences,2009

3. Review of T-wave morphology-based biomarkers of ventricular repolarisation using the surface electrocardiogram;TP Brennan;Biomedical Signal Processing and Control,2012

4. T(p-e)/QT ratio as an index of arrhythmogenesis;P Gupta;Journal of Electrocardiology,2008

5. Jie X, Rodriguez B, Pueyo E. A new ECG biomarker for drug toxicity: A combined signal processing and computational modeling study. In: Proc. Annual Int. Conf. of the IEEE Engineering in Medicine and Biology; 2010. p. 2565–2568.

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