Oncogenic Kit Triggers Shp2/Erk1/2 Pathway to Down-Regulate the Pro-Apoptotic Protein Bim and to Promote Apoptosis Resistance in Leukemic Cells
Author:
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference28 articles.
1. Spi-1/PU.1 transgenic mice develop multistep erythroleukemias;F Moreau-Gachelin;Mol Cell Biol,1996
2. The c-KIT mutation causing human mastocytosis is resistant to STI571 and other KIT kinase inhibitors; kinases with enzymatic site mutations show different inhibitor sensitivity profiles than wild-type kinases and those with regulatory-type mutations;Y Ma;Blood,2002
3. Effects of tyrosine kinase inhibitor STI571 on human mast cells bearing wild-type or mutated c-kit;C Akin;Exp Hematol,2003
4. Cotargeting signaling pathways driving survival and cell cycle circumvents resistance to Kit inhibitors in leukemia;D Buet;Blood,2012
5. Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity;SM Maira;Mol Cancer Ther,2008
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2. SLAM family member 8 is involved in oncogenic KIT-mediated signalling in human mastocytosis;Experimental Dermatology;2018-06
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