Effect of Benfotiamine on Advanced Glycation Endproducts and Markers of Endothelial Dysfunction and Inflammation in Diabetic Nephropathy

Author:

Alkhalaf Alaa,Kleefstra Nanne,Groenier Klaas H.,Bilo Henk J. G.,Gans Reinold O. B.,Heeringa Peter,Scheijen Jean L.,Schalkwijk Casper G.,Navis Gerjan J.,Bakker Stephan J. L.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference16 articles.

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2. Prevention of incipient diabetic nephropathy by high-dose thiamine and benfotiamine. Diabetes.;R Babaei-Jadidi,2003

3. Increased protein damage in renal glomeruli, retina, nerve, plasma and urine and its prevention by thiamine and benfotiamine therapy in a rat model of diabetes. Diabetologia.;N Karachalias,2010

4. Benfotiamine blocks three major pathways of hyperglycemic damage and prevents experimental diabetic retinopathy. Nat Med.;HP Hammes,2003

5. High-dose thiamine therapy for patients with type 2 diabetes and microalbuminuria: A randomised, double-blind placebo-controlled pilot study. Diabetologia.;N Rabbani,2009

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