Rhodacyanine Derivative Selectively Targets Cancer Cells and Overcomes Tamoxifen Resistance

Author:

Koren John,Miyata Yoshinari,Kiray Janine,O'Leary John C.,Nguyen Lana,Guo Jianping,Blair Laura J.,Li Xiokai,Jinwal Umesh K.,Cheng Jin Q.,Gestwicki Jason E.,Dickey Chad A.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference27 articles.

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2. A phase I and pharmacokinetic study of the mitochondrial-specific rhodacyanine dye analog MKT 077.;CD Britten;Clin Cancer Res,2000

3. Phase I trial of the selective mitochondrial toxin MKT077 in chemo-resistant solid tumours.;DJ Propper;Ann Oncol,1999

4. Selective toxicity of MKT-077 to cancer cells is mediated by its binding to the hsp70 family protein mot-2 and reactivation of p53 function.;R Wadhwa;Cancer Res,2000

5. Inactivation of tumor suppressor p53 by mot-2, a hsp70 family member.;R Wadhwa;J Biol Chem,1998

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