The MTH1 inhibitor TH588 demonstrates anti-tumoral effects alone and in combination with everolimus, 5-FU and gamma-irradiation in neuroendocrine tumor cells
Author:
Funder
FAZIT Stiftung
Publisher
Public Library of Science (PLoS)
Subject
Multidisciplinary
Reference51 articles.
1. Oxidative stress, inflammation, and cancer: how are they linked?;S Reuter;Free radical biology & medicine,2010
2. Oxidative stress and oxidative damage in carcinogenesis;JE Klaunig;Toxicologic pathology,2010
3. Long-term effects of systemic cancer treatment on DNA oxidative damage: the potential for targeted therapies;L Vera-Ramirez;Cancer Lett,2012
4. Redox regulation of DNA repair: implications for human health and cancer therapeutic development;M Luo;Antioxidants & redox signaling,2010
5. Oxidative stress, DNA damage and repair in carcinogenesis: have we established a connection?;AG Georgakilas;Cancer Lett,2012
Cited by 11 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献
1. Human MutT Homolog 1 (MTH1) Inhibitor Reduces the Biological Activity of Ovarian Carcinoma Cells;Journal of Biomaterials and Tissue Engineering;2022-05-01
2. Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML;Molecular Cancer Therapeutics;2022-02-28
3. MutT Homolog1 has multifaceted role in glioma and is under the apparent orchestration by Hypoxia Inducible factor1 alpha;Life Sciences;2021-01
4. Targeting the nucleotide metabolism proteins of the NUDIX family and SAMHD1 in cancer;Current Medicinal Chemistry;2020-11-25
5. hMTH1 and GPX1 expression in human thyroid tissue is interrelated to prevent oxidative DNA damage;DNA Repair;2020-11
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3