Real-time cell toxicity profiling of Tox21 10K compounds reveals cytotoxicity dependent toxicity pathway linkage

Author:

Hsieh Jui-HuaORCID,Huang Ruili,Lin Ja-An,Sedykh Alexander,Zhao Jinghua,Tice Raymond R.,Paules Richard S.,Xia Menghang,Auerbach Scott S.

Publisher

Public Library of Science (PLoS)

Subject

Multidisciplinary

Reference40 articles.

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2. Screening Chemicals for Estrogen Receptor Bioactivity Using a Computational Model;P Browne;Environ Sci Technol,2015

3. Predictive Endocrine Testing in the 21st Century Using in Vitro Assays of Estrogen Receptor Signaling Responses;DM Rotroff;Environ Sci Technol,2014

4. Sipes NS, Wambaugh JF, Pearce R, Auerbach SS, Hsieh J-H, Shapiro AJ, et al. An Intuitive Approach for Predicting Potential Human Health Risk with the Tox21 10k Library. Environ Sci Technol. Under Revision.

5. Cell death assays for drug discovery;O Kepp;Nat Rev Drug Discov,2011

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