Oxidation of Helix-3 Methionines Precedes the Formation of PK Resistant PrPSc

Author:

Canello Tamar,Frid Kati,Gabizon Ronen,Lisa Silvia,Friedler Assaf,Moskovitz Jackob,Gasset María,Gabizon Ruth

Publisher

Public Library of Science (PLoS)

Subject

Virology,Genetics,Molecular Biology,Immunology,Microbiology,Parasitology

Reference55 articles.

1. Prion protein biology.;SB Prusiner;Cell,1998

2. Neurodegeneration and oxidative stress: prion disease results from loss of antioxidant defence.;DR Brown;Folia Neuropathol,2005

3. Prion protein does not redox-silence Cu2+, but is a sacrificial quencher of hydroxyl radicals.;RC Nadal;Free Radic Biol Med,2007

4. Antioxidant activity related to copper binding of native prion protein.;DR Brown;J Neurochem,2001

5. Copper-dependent functions for the prion protein.;DR Brown;Mol Biotechnol,2002

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