Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography-Reference-Cited by-同舟云学术

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Designed mono- and di-covalent inhibitors trap modeled functional motions for Trypanosoma cruzi proline racemase in crystallography

Published:2018-10-29 Issue:10 Volume:12 Page:e0006853
ISSN:1935-2735
Container-title:PLOS Neglected Tropical Diseases
language:en
Short-container-title:PLoS Negl Trop Dis

Author:

Amaral Patricia de Aguiar,Autheman Delphine,de Melo Guilherme Dias^ORCID,Gouault Nicolas,Cupif Jean-François,Goyard Sophie^ORCID,Dutra Patricia,Coatnoan Nicolas,Cosson Alain,Monet Damien,Saul Frederick,Haouz Ahmed^ORCID,Uriac Philippe,Blondel Arnaud,Minoprio Paola^ORCID

Funder

Fondation pour la Recherche Médicale

Agence Nationale de la Recherche

Association Instituts Carnot (FR)

CAPES

PTR- Institut Pasteur

FRM

Publisher

Public Library of Science (PLoS)

Subject

Infectious Diseases,Public Health, Environmental and Occupational Health

Reference54 articles.

1. The burden of Neglected Tropical Diseases in Brazil, 1990–2016: A subnational analysis from the Global Burden of Disease Study 2016;FR Martins-Melo;PLOS Neglected Tropical Diseases,2018

2. Neglected Diseases;D. O'Connell;Nature,2007

3. Andean subregional Chagas disease area and the Andean initiative of Chagas disease;R. Salvatella;Memorias do Instituto Oswaldo Cruz,2007

4. Immunotherapy of Trypanosoma cruzi infections;N Chamond;Current drug targets Immune, endocrine and metabolic disorders,2002

5. Nitro drugs for the treatment of trypanosomatid diseases: past, present, and future prospects;S Patterson;Trends in Parasitology,2014

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1. (Photo)affinity Label and Covalent Inhibitor Design;Active Site-directed Enzyme Inhibitors;2023-09-13

2. Covalent Inhibitors for Neglected Diseases: An Exploration of Novel Therapeutic Options;Pharmaceuticals;2023-07-19

3. Design and evaluation of substrate–product analog inhibitors for racemases and epimerases utilizing a 1,1-proton transfer mechanism;Methods in Enzymology;2023

4. Prodrugs as new therapies against Chagas disease: in vivo synergy between Trypanosoma cruzi proline racemase inhibitors and benznidazole;Journal of Global Antimicrobial Resistance;2022-03

5. Irreversible inhibitors of the proline racemase unveil innovative mechanism of action as antibacterial agents against Clostridioides difficile;Chemical Biology & Drug Design;2022-01-05

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