Polysaccharide from black currant (Ribes nigrum L.) stimulates dendritic cells through TLR4 signaling

Author:

ASHIGAI Hiroshi1,KOMANO Yuta1,WANG Guanying1,KAWACHI Yasuji1,SUNAGA Kazuko2,YAMAMOTO Reiko3,TAKATA Ryoji3,MIYAKE Mika1,YANAI Takaaki3

Affiliation:

1. Research Laboratories for Health Science & Food Technologies, Kirin Company, Ltd., 1-17-1 Namamugi, Tsurumi-ku, Yokohama 230-8628, Japan

2. Marketing Department, Mercian Corporation, 4-10-2 Nakano, Nakano-ku, Tokyo 164-0001, Japan

3. Research Laboratories for Wine Technologies, Kirin Company, Ltd., 4-9-1 Johnan, Fujisawa 251-0057, Japan

Publisher

BMFH Press

Subject

Gastroenterology,Applied Microbiology and Biotechnology,Immunology,Microbiology,Food Science

Reference30 articles.

1. 1. Gopalan A, Reuben SC, Ahmed S, Darvesh AS, Hohmann J, Bishayee A. 2012. The health benefits of blackcurrants. Food Funct 3: 795–809.

2. 2. Nakamura Y, Matsumoto H, Todoki K. 2002. Endothelium-dependent vasorelaxation induced by black currant concentrate in rat thoracic aorta. Jpn J Pharmacol 89: 29–35.

3. 3. Knox YM, Suzutani T, Yosida I, Azuma M. 2003. Anti-influenza virus activity of crude extract of Ribes nigrum L. Phytother Res 17: 120–122.

4. 4. Iida H, Nakamura Y, Matsumoto H, Kawahata K, Koga J, Katsumi O. 2013. Differential effects of black currant anthocyanins on diffuser- or negative lens-induced ocular elongation in chicks. J Ocul Pharmacol Ther 29: 604–609.

5. 5. Takata R, Yamamoto R, Yanai T, Konno T, Okubo T. 2005. Immunostimulatory effects of a polysaccharide-rich substance with antitumor activity isolated from black currant (Ribes nigrum L.). Biosci Biotechnol Biochem 69: 2042–2050.

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