Characteristics of the enteroaggregative Shiga toxin/verotoxin-producing Escherichia coli O104:H4 strain causing the outbreak of haemolytic uraemic syndrome in Germany, May to June 2011-Reference-Cited by-同舟云学术

Characteristics of the enteroaggregative Shiga toxin/verotoxin-producing Escherichia coli O104:H4 strain causing the outbreak of haemolytic uraemic syndrome in Germany, May to June 2011

Published:2011-06-16 Issue:24 Volume:16 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Scheutz F¹²,Møller Nielsen E¹,Frimodt-Møller J³²,Boisen N¹²,Morabito S⁴,Tozzoli R⁴,Nataro J P⁵,Caprioli A⁴

Affiliation:

1. Food-borne pathogens and typing, Department of Microbiological Surveillance and Research, Statens Serum Institut, Copenhagen, Denmark

2. World Health Organization Collaborating Centre for Reference and Research on Escherichia and Klebsiella, Department of Microbiological Surveillance and Research, Copenhagen, Denmark

3. Department of Clinical Microbiology, Hillerød Sygehus, Hillerød, Denmark

4. European Union Reference Laboratory for Escherichia coli, Department of veterinary public health and food safety, Istituto Superiore di Sanità, Rome, Italy

5. University of Virginia School of Medicine, Charlottesville, United States

Abstract

The Escherichia coli strain causing a large outbreak of haemolytic uraemic syndrome and bloody diarrhoea in Germany in May and June 2011 possesses an unusual combination of pathogenic features typical of enteroaggregative E. coli together with the capacity to produce Shiga toxin. Through rapid national and international exchange of information and strains the known occurrence in humans was quickly assessed. We describe simple diagnostic screening tools to detect the outbreak strain in clinical specimens and a novel real-time PCR for its detection in foods.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Cited by 164 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Genomic Dissection of an Enteroaggregative Escherichia coli Strain Isolated from Bacteremia Reveals Insights into Its Hybrid Pathogenic Potential;International Journal of Molecular Sciences;2024-08-26

2. Infection of mice by the enteroaggregative E. coli strain 042 and two mutant derivatives overexpressing virulence factors: impact on disease markers, gut microbiota and concentration of SCFAs in feces;Scientific Reports;2024-07-23

3. Comparative Evaluation of Loop-Mediated Isothermal Amplification (LAMP) and Conventional PCR for Detection of Shiga-Toxin-Producing <i>Escherichia coli</i> (STEC) in Various Food Products;Journal of Food Hygiene and Safety;2023-10-30

4. Identification and Characterization of ten Escherichia coli Strains Encoding Novel Shiga Toxin 2 Subtypes, Stx2n as Well as Stx2j, Stx2m, and Stx2o, in the United States;Microorganisms;2023-10-14

5. Transforming Shiga toxin-producing Escherichia coli surveillance through whole genome sequencing in food safety practices;Frontiers in Microbiology;2023-07-13