A surge of MDR and XDR tuberculosis in France among patients born in the Former Soviet Union

Author:

Bernard C123,Brossier F132,Sougakoff W231,Veziris N123,Frechet-Jachym M4,Metivier N4,Renvoisé A123,Robert J132,Jarlier V231,on behalf of the MDR-TB Management group of the NRC collective5

Affiliation:

1. Laboratory of Bacteriology and Hygiene, Hôpital Pitié-Salpêtrière, AP-HP, Paris, France

2. UPMC Paris 06 (Pierre and Marie Curie University Paris), ER 5, EA 1541, Laboratoty of Bacteriology and Hygiene, Paris, France

3. Centre National de Référence des Mycobactéries et de la Résistance des Mycobactéries aux Antituberculeux (National reference centre for mycobacteria and resistance of micobacteria to antituberculous drugs), Paris, France

4. Medical Centre of Bligny, Briis sous Forges, France

5. The members of the team are listed at the end of the article

Abstract

A marked increase in the number of multidrug-resistant (MDR) tuberculosis (TB) cases entirely related to patients born in the Former Soviet Union was observed in France in the last two years. Very few cases were clustered, suggesting it is a consequence of recent immigration of patients already infected in their country of origin. This major increase challenges the existing structures for management of MDR and extensively drug-resistant TB (XDR-TB).

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference19 articles.

1. World Health Organization (WHO). Global tuberculosis report 2012. Geneva: WHO; 2012. Available from: http://www.who.int/tb/publications/global_report/en/index.html

2. Surveillance of anti-tuberculosis drug resistance in the world: an updated analysis, 2007–2010

3. Dewan P, Sosnovskaja A, Thomsen V, Cicenaite J, Laserson K, Johansen I, et al. High prevalence of drug-resistant tuberculosis, Republic of Lithuania, 2002. Int J Tuberc Lung Dis. 2005;9(2):170-4. PMid:15732736

4. Tuberculosis trends in Eastern Europe and the former USSR

5. Alarming levels of drug-resistant tuberculosis in Belarus: results of a survey in Minsk

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