Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018-Reference-Cited by-同舟云学术

Detection in the United Kingdom of the Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate resistance to azithromycin, October to December 2018

Published:2019-03-07 Issue:10 Volume:24 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Eyre David W¹²,Town Katy³,Street Teresa¹,Barker Leanne¹,Sanderson Nicholas¹,Cole Michelle J³,Mohammed Hamish³,Pitt Rachel³,Gobin Maya³,Irish Charles³,Gardiner Daniel³,Sedgwick James³,Beck Charles³,Saunders John³,Turbitt Deborah³,Cook Clare³,Phin Nick³,Nathan Bavithra⁴³,Horner Paddy⁴⁵³,Fifer Helen⁴³

Affiliation:

1. Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

2. Big Data Institute, University of Oxford, Oxford, United Kingdom

3. National Incident Management Team, Public Health England, London, United Kingdom

4. These authors contributed equally to this work

5. Population Health Sciences, University of Bristol, Bristol, United Kingdom

Abstract

We describe detection in the United Kingdom (UK) of the drug-resistant Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference23 articles.

1. New ceftriaxone- and multidrug-resistant Neisseria gonorrhoeae strain with a novel mosaic penA gene isolated in Japan.;Nakayama;Antimicrob Agents Chemother,2016

2. Genomic surveillance of Neisseria gonorrhoeae to investigate the distribution and evolution of antimicrobial-resistance determinants and lineages.;Yahara;Microb Genom,2018

3. Cooperative Recognition of Internationally Disseminated Ceftriaxone-Resistant Neisseria gonorrhoeae Strain.;Lahra;Emerg Infect Dis,2018

4. Ceftriaxone-Resistant Neisseria gonorrhoeae, Canada, 2017.;Lefebvre;Emerg Infect Dis,2018

5. Multidrug-resistant Neisseria gonorrhoeae infection with ceftriaxone resistance and intermediate resistance to azithromycin, Denmark, 2017.;Terkelsen;Euro Surveill,2017

Cited by 121 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. CRISPR-based platform for clinical diagnosis of Neisseria gonorrhoeae and simultaneous tracking of ceftriaxone-resistant FC428 clone;Chemical Engineering Journal;2024-10

2. Longitudinal genomic analysis of Neisseria gonorrhoeae transmission dynamics in Australia;Nature Communications;2024-09-14

3. High-level ceftriaxone resistance due to transfer of penA allele 60.001 into endemic gonococcal lineages in Hangzhou, China;Journal of Antimicrobial Chemotherapy;2024-08-26

4. Ceftriaxone-resistantNeisseria gonorrhoeaedetected in England, 2015 to 2024; an observational study;2024-08-17

5. Managing treatment failure in Neisseria gonorrhoeae infection: current guidelines and future directions;The Lancet Infectious Diseases;2024-08