Increase in invasive group A streptococcal infection notifications, England, 2022

Author:

Guy Rebecca1ORCID,Henderson Katherine L1ORCID,Coelho Juliana2,Hughes Helen3,Mason Emily L1,Gerver Sarah M1,Demirjian Alicia451,Watson Conall6,Sharp Ashley1,Brown Colin S1,Lamagni Theresa1

Affiliation:

1. HCAI, Fungal, AMR, AMU and Sepsis Division, UK Health Security Agency, London, United Kingdom

2. Staphylococcus and Streptococcus Reference Section, AMRHAI, UK Health Security Agency, London, United Kingdom

3. Real-time Syndromic Surveillance Team, Field Services Division, UK Health Security Agency, London, United Kingdom

4. Faculty of Life Sciences & Medicine, King’s College London, London, United Kingdom

5. Department of Paediatric Infectious Diseases & Immunology, Evelina London Children’s Hospital, London, United Kingdom

6. Immunisation and Vaccine-Preventable Diseases Division, UK Health Security Agency, London, United Kingdom

Abstract

Increases in invasive group A streptococcal (iGAS) infection and associated deaths, particularly in children, above seasonally expected levels are being seen this season (772 notifications reported in weeks 37 to 48 in 2022) across England. Diagnoses of iGAS infection from lower respiratory tract specimens in children under 15 years increased to 28% in November 2022. Medical practitioners have been alerted to the exceptional increase in incidence, including unusual numbers of children presenting with pulmonary empyema.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference17 articles.

1. UK Health Security Agency (UKHSA). GP in-hours consultations bulletin: 8 December 2022 week 48. London: UKHSA; 2022. Available from: https://www.gov.uk/government/publications/gp-in-hours-weekly-bulletins-for-2022

2. UK Health Security Agency (UKHSA). Group A streptococcal infections: update on seasonal activity in England, 2021 to 2022. London: UKHSA; 2022. Available from: https://www.gov.uk/government/publications/group-a-streptococcal-infections-activity-during-the-2021-to-2022-season/group-a-streptococcal-infections-update-on-seasonal-activity-in-england-2021-to-2022

3. Department of Health and Social Care (DHSC). Health protection legislation (England) guidance 2010. London: DHSC; 2010. Available from: https://webarchive.nationalarchives.gov.uk/ukgwa/20130105053557/http:/www.dh.gov.uk/prod_consum_dh/groups/dh_digitalassets/@dh/@en/@ps/documents/digitalasset/dh_114589.pdf

4. UK Health Security Agency (UKHSA). UK guidelines for the management of contacts of invasive group A streptococcus (iGAS) infection in community settings. London: UKHSA; 2022. Available from: https://www.gov.uk/government/publications/invasive-group-a-streptococcal-disease-managing-community-contacts

5. UK Health Security Agency (UKHSA). Group A streptococcal infections: first update on seasonal activity in England, 2022 to 2023. London: UKHSA; 2022. Available from: https://www.gov.uk/government/publications/group-a-streptococcal-infections-activity-during-the-2022-to-2023-season/group-a-streptococcal-infections-first-update-on-seasonal-activity-in-england-2022-to-2023

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