Repeated leftover serosurvey of SARS-CoV-2 IgG antibodies, Greece, March and April 2020

Author:

Bogogiannidou Zacharoula1,Vontas Alexandros1,Dadouli Katerina1,Kyritsi Maria A1,Soteriades Soteris1,Nikoulis Dimitrios J1,Mouchtouri Varvara Α1,Koureas Michalis1,Kazakos Evangelos I2,Spanos Emmanouil G1,Gioula Georgia3,Ntzani Evangelia E456,Eleftheriou Alexandros A6,Vatopoulos Alkiviadis7,Petinaki Efthimia8,Papaevangelou Vassiliki9,Speletas Matthaios10,Tsiodras Sotirios11,Hadjichristodoulou Christos1

Affiliation:

1. Laboratory of Hygiene and Epidemiology, Faculty of Medicine, University of Thessaly, Larissa, Greece

2. Faculty of Midwifery, School of Health Sciences, University of Western Macedonia, Kozani, Greece

3. National Influenza Reference Laboratory for Northern Greece, Microbiology Department, Medical School, Aristotle University of Thessaloniki, Thessaloniki, Greece

4. Institute of Biosciences, University Research Center of loannina, Ioannina, Greece

5. Center for Evidence Synthesis in Health, Department of Health Services, Policy and Practice, School of Public Health, Brown University, Providence, United States

6. Department of Hygiene and Epidemiology, University of Ioannina Faculty of Medicine, Ioannina, Greece

7. Department of Public Health Policy, School of Public Health, University of West Attica, Athens, Greece

8. Department of Microbiology, University Hospital of Larissa, University of Thessaly, Larissa, Greece

9. Third Department of Paediatrics, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece

10. Department of Immunology and Histocompatibility, Faculty of Medicine, University of Thessaly, Larissa, Greece

11. Fourth Department of Internal Medicine, National and Kapodistrian University of Athens, School of Medicine, Attikon University Hospital, Athens, Greece

Abstract

A serosurvey of IgG antibodies against severe acute respiratory coronavirus 2 (SARS-CoV-2) was performed during March and April 2020. Among 6,586 leftover sera, 24 (0.36%) were positive, with higher prevalence in females, older individuals and residents of large urban areas. Seroprevalence was estimated at 0.02% and 0.25%, respectively, in March and April, infection fatality rate at 2.66% and 0.54%. Our findings confirm low COVID-19 incidence in Greece and possibly the effectiveness of early measures.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

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