Cases of Crimean-Congo haemorrhagic fever in North Macedonia, July to August 2023

Author:

Jakimovski Dejan123ORCID,Grozdanovski Krsto23,Rangelov Goran2,Pavleva Verica4,Banović Pavle156ORCID,Cabezas-Cruz Alejandro7ORCID,Spasovska Katerina23

Affiliation:

1. These authors contributed equally to the work and share first authorship

2. University Clinic for Infectious Diseases and Febrile Conditions, Skopje, Republic of North Macedonia

3. Faculty of Medicine, Ss. Cyril and Methodius University in Skopje, Skopje, Republic of North Macedonia

4. Infectious Disease Department, Clinical Hospital Shtip, Shtip, Republic of North Macedonia

5. Department of Microbiology with Parasitology and Immunology, Faculty of Medicine in Novi Sad, University of Novi Sad, Novi Sad, Serbia

6. Clinic for Lyme Borreliosis and Other Tick-Borne Diseases, Pasteur Institute Novi Sad, Novi Sad, Serbia

7. Anses, INRAE, Ecole Nationale Vétérinaire d’Alfort, UMR BIPAR, Laboratoire de Santé Animale, Maisons-Alfort, France

Abstract

The last report of Crimean-Congo haemorrhagic fever (CCHF) in North Macedonia was more than 50 years ago in the northwest. We report on a fatal CCHF case following a Hyalomma tick bite in the east of the country in July 2023. Tracing of 67 contacts identified CCHF in one healthcare worker (HCW) providing care for the patient. Monitoring of contacts is concluded (including further 11 HCW contacts), thus far 28 days after the death of the case no additional cases were identified.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference16 articles.

1. World Health Organization (WHO). Prioritizing diseases for research and development in emergency contexts. Geneva: WHO; 24 March 2023. [Accessed 1 Aug 2023]. Available from: https://www .who.int/activities/prioritizing-diseases-for-research-and-development-in-emergency-contexts

2. Epidemic intelligence data of Crimean-Congo haemorrhagic fever, European Region, 2012 to 2022: a new opportunity for risk mapping of neglected diseases.;Fanelli;Euro Surveill,2023 

3. Institute of Public Health of the Republic of North Macedonia (IPHNM). Информација за потврден случај на Конго-Кримска хеморагична треска. [Information on a confirmed case of Crimean-Congo haemorrhagic fever]. Skopje: IPHNM; 2023. Macedonian. Available from: https://www.iph.mk/informacija-2/

4. MSF (Medicins sans frontières). Clinical guidelines – diagnosis and treatment manual. Chapter 8 Viral diseases – Viral haemorrhagic fevers. Geneva: MSF. [Accessed: 26 July 2023]. Available from: https://medicalguidelines .msf.org/en/viewport/CG/nglish/viral-haemorrhagic-fevers-16690024.html

5. Crimean-Congo haemorrhagic fever virus.;Hawman;Nat Rev Microbiol,2023

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