Epidemic of parvovirus B19 and disease severity in pregnant people, Denmark, January to March 2024

Author:

Nordholm Anne Christine1ORCID,Trier Møller Frederik1ORCID,Fischer Ravn Signe2,Flink Sørensen Lotte2,Moltke-Prehn Anja2ORCID,Elskær Mollerup Jacob2,Funk Tjede1ORCID,Sperling Lene3,Jeyaratnam Ulisa1,Træholt Franck Kristina4ORCID,Hjort-Pedersen Karina3,Hjørnet Kamper Christina5,Thoft Nielsen Rikke2,Jokelainen Pikka6ORCID,Wessman Maria1ORCID

Affiliation:

1. Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark

2. Department of Data Integration and Analysis, Statens Serum Institut, Copenhagen, Denmark

3. Department of Gynaecology and Obstetrics, Odense University Hospital, Odense, Denmark

4. Department of Virus and Microbiological Special Diagnostics, Statens Serum Institut, Copenhagen, Denmark

5. Department of Gynaecology and Obstetrics, Aarhus University Hospital, Aarhus, Denmark

6. Infectious Disease Preparedness, Statens Serum Institut, Copenhagen, Denmark

Abstract

We report an epidemic of parvovirus B19 infections in Denmark during the first quarter of 2024, with a peak incidence 3.5 times higher than during the most recent epidemic in 2017. In total, 20.1% (130/648) of laboratory-confirmed cases were pregnant. Severe adverse outcomes were observed among 12.3% (16/130) of pregnant people and included foetal anaemia, foetal hydrops and miscarriage. Parvovirus B19 infection is not systematically monitored, but a national laboratory-based surveillance system is currently being established in Denmark.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Reference16 articles.

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2. Parvovirus B19 infection in five European countries: seroepidemiology, force of infection and maternal risk of infection.;Mossong;Epidemiol Infect,2008

3. Risk factors for parvovirus B19 infection in pregnancy.;Valeur-Jensen;JAMA,1999

4. Statens Serum Institut (SSI). Parvovirus B19 and pregnancy. Epi-News, no. 13 2024. Copenhagen: SSI; 10 Apr 2024. Available from: https://en.ssi.dk/news/epi-news/2024/no-13---2024

5. Parvovirus B19 and the pathogenesis of anaemia.;Chisaka;Rev Med Virol,2003

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