Undeclared pre-exposure or post-exposure prophylaxis (PrEP/PEP) use among syphilis-positive blood donors, England, 2020 to 2021-Reference-Cited by-同舟云学术

Undeclared pre-exposure or post-exposure prophylaxis (PrEP/PEP) use among syphilis-positive blood donors, England, 2020 to 2021

Published:2023-03-16 Issue:11 Volume:28 Page:
ISSN:1560-7917
Container-title:Eurosurveillance
language:en
Short-container-title:

Author:

Maddox Victoria¹,Reynolds Claire²,Amara Alieu³,Else Laura³,Brailsford Susan R⁴²¹,Khoo Saye³,Harvala Heli⁵¹

Affiliation:

1. Microbiology Services, NHS Blood and Transplant, London, United Kingdom

2. NHS Blood and Transplant/UK Health Security Agency Epidemiology Unit, NHS Blood and Transplant, London, United Kingdom

3. Department of Pharmacology, University of Liverpool, Liverpool, United Kingdom

4. National Infection Service, United Kingdom Health Security Agency, London, United Kingdom

5. Infection and Immunity, University College London, London, United Kingdom

Abstract

An individualised blood donor selection policy was implemented in the United Kingdom from summer 2021. We have investigated the impact of this policy by comparing the extent of undeclared use of HIV pre-exposure or post-exposure prophylaxis (PrEP/PEP) before and after this change. The rate of PrEP usage in syphilis-positive male blood donors has not changed since individualised donor assessment was implemented but provides continuing evidence of undisclosed PrEP use which may be associated with current or past higher-risk sexual behaviours.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference15 articles.

1. Advisory Committee on the Safety of Blood. Tissues and Organs (SaBTO). Can donor selection policy move from a population-based donor selection policy to one based on a more individualised risk assessment? Conclusions from the For the Assessment of Individualised Risk (FAIR) group. SaBTO; 2020. Available from: https://nhsbtdbe.blob.core.windows.net/umbraco-assets-corp/21001/fair_sabto_20201211.pdf

2. Effectiveness of interventions aimed at reducing HIV acquisition and transmission among gay and bisexual men who have sex with men (GBMSM) in high income settings: A systematic review.;Sewell;PLoS One,2022

3. Joint United Kingdom Blood Transfusion and Tissue Transplantation Services Professional Advisory Committee (JPAC). Change notification No. 04 – 2019. Pre- and post-exposure prophylaxis for HIV prevention– applies to the whole blood and components donor selection guidelines. Sheffield: JPAC; 2019. Available from https://www.transfusionguidelines.org/document-library/change-notifications/change-notifications-issued-in-2019

4. Evidence of HIV pre-exposure or post-exposure prophylaxis (PrEP/PEP) among blood donors: a pilot study, England June 2018 to July 2019.;Harvala;Sex Transm Infect,2022

5. Lessons learnt from syphilis-infected blood donors: a timely reminder of missed opportunities.;Harvala;Sex Transm Infect,2022

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