Middle East respiratory syndrome coronavirus (MERS-CoV) RNA and neutralising antibodies in milk collected according to local customs from dromedary camels, Qatar, April 2014

Author:

Reusken C B12,Farag E A23,Jonges M24,Godeke G J4,El-Sayed A M3,Pas S D1,Raj V S1,Mohran K A5,Moussa H A6,Ghobashy H5,Alhajri F5,Ibrahim A K67,Bosch B J8,Pasha S K6,Al-Romaihi H E3,Al-Thani M3,Al-Marri S A3,AlHajri M M3,Haagmans B L1,Koopmans M P41

Affiliation:

1. Erasmus Medical Center, Rotterdam, the Netherlands

2. These authors contributed equally to the manuscript.

3. Supreme Council of Health, Doha, Qatar

4. Netherlands Centre for Infectious Disease Control, National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands

5. Ministry of Environment, Doha, Qatar

6. Leawaina camel hospital, Dukhan, Qatar

7. Faculty of Veterinary Medicine, Cairo University, Cairo, Egypt

8. Faculty of Veterinary Medicine, Utrecht University, Utrecht, the Netherlands

Abstract

Antibodies to Middle East respiratory syndrome coronavirus (MERS-CoV) were detected in serum and milk collected according to local customs from 33 camels in Qatar, April 2014. At one location, evidence for active virus shedding in nasal secretions and/or faeces was observed for 7/12 camels; viral RNA was detected in milk of five of these seven camels. The presence of MERS-CoV RNA in milk of camels actively shedding the virus warrants measures to prevent putative food-borne transmission of MERS-CoV.

Publisher

European Centre for Disease Control and Prevention (ECDC)

Subject

Virology,Public Health, Environmental and Occupational Health,Epidemiology

Reference27 articles.

1. Middle East respiratory syndrome coronavirus in dromedary camels: an outbreak investigation

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3. World Health Organization (WHO). Middle East respiratory syndrome coronavirus (MERS-CoV) – update. Geneva: WHO; 2014. [Accessed 12 Jun 2014]. Available from: http://www.who.int/csr/don/2014_06_11_mers/en/

4. European Centre for Disease Prevention and Contro (ECDC). Severe respiratory disease associated with Middle East respiratory syndrome coronavirus (MERS-CoV) – tenth update, 31 May 2014. Stockholm: ECDC; 2014. Available from: http://www.ecdc.europa.eu/en/publications/Publications/RRA-Middle-East-respiratory-syndrome-coronavirus-update10.pdf

5. World Health Organization (WHO). Middle East respiratory syndrome coronavirus (MERS-CoV). summary and literature update–as of 9 May 2014. Geneva: WHO; 2014. [Accessed 29 May 2014]. Available from: http://www.who.int/csr/disease/coronavirus_infections/MERS_CoV_Update_09_May_2014.pdf

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