The control of blood platelets by cAMP signalling-Reference-Cited by-同舟云学术

The control of blood platelets by cAMP signalling

Published:2014-03-20 Issue:2 Volume:42 Page:289-294
ISSN:0300-5127
Container-title:Biochemical Society Transactions
language:en
Short-container-title:

Author:

Raslan Zaher¹,Naseem Khalid M.¹

Affiliation:

1. Centre for Cardiovascular and Metabolic Research, Hull York Medical School, University of Hull, Cottingham Road, Hull HU6 7RX, U.K.

Abstract

Blood platelet activation must be tightly regulated to ensure a balance between haemostasis and thrombosis. The cAMP signalling pathway is the most powerful endogenous regulator of blood platelet activation. PKA (protein kinase A), the foremost effector of cAMP signalling in platelets, phosphorylates a number of proteins that are thought to modulate multiple aspects of platelet activation. In the present mini-review, we outline our current understanding of cAMP-mediated platelet inhibition and discuss some of the issues that require clarification.

Publisher

Portland Press Ltd.

Subject

Biochemistry

Link

https://portlandpress.com/biochemsoctrans/article-pdf/42/2/289/487366/bst0420289.pdf

Reference45 articles.

1. The growing complexity of platelet aggregation;Jackson;Blood,2013

2. Taming platelets with cyclic nucleotides;Schwarz;Biochem. Pharmacol.,2001

3. Physiological roles for G protein-regulated adenylyl cyclase isoforms: insights from knockout and overexpression studies;Sadana;Neurosignals,2009

4. Gi2 mediates α2-adrenergic inhibition of adenylyl cyclase in platelet membranes: in situ identification with Gα C-terminal antibodies;Simonds;Proc. Natl. Acad. Sci. U.S.A.,1989

5. Genome-wide RNA-seq analysis of human and mouse platelet transcriptomes;Rowley;Blood,2011

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