An In Vitro Study of Histology of Nonfluorosed and Fluorosed Bone

Abstract

The study of the epidemiologic association between fluorosis and periodontitis, as well as the effects of fluorosis on periodontal tissues and the effects of periodontal therapy on teeth of non-fluorosed and fluorosed. There has been limited research into the effects of fluorosis on organic tissues for example bones.  The biomechanical, histology and biochemical properties of fluorosed bones have still not been studied in alveolar bone, which, like extremities, is an important component of the periodontal tissue. Objective: The goal of this research was to compare the histology of fluorosed femur bones to that of non-fluorosed femur bones. Method: 40 non-fluorosed and fluorosed healthy bone (femoral) samples were tested using a microscope to compare and assess the histology of non-fluorosed with fluorosed bone. Results: When comparing the non-fluorosed group (11.835.21, 9.853.45) to the fluorosed group (7.724.42, 6.702.42), bone of cortical and cancellous cellularity was shown to be substantial in term of statistics. The non-fluorosed and fluorosed bone had the same trabecular density statistically not significant, p-value is equal to 0.726]. Nonfluorosed bone had thick trabeculae, while fluorosed bone had short and thin trabeculae. Conclusion: The identified histologic variations could affect the pathogenesis of periodontitis / the efficacy of periodontal therapy. In widespread fluorosed regions, dental fluoride could likely be identified as an important public health issue.