Clinical Implication of Hepatic Phosphatases in Hyperthyroidism

Abstract

Thyroid hormones significantly affect the proper growth, development and functioning of liver. It has been seen that the drugs indicated for thyroid abnormalities also cause troubles in liver function. Objective: To check the effect of thyroid abnormality on liver function. Methods: Patients were recruited from Center of Nuclear Medicine and examined for their thyroid status and liver functions. Results: The results obtained through biochemical tests for potential biomarkers were further explored through statistical analysis which showed the strong correlation between disturbed function of thyroid gland and liver working. Any variation in thyroid function brings change in liver functioning. Conclusions: Therefore, while treating thyroid patients, combination therapy must be recommended to effectively treat the associated disorder and increasing the better social and psychological status of the patient.  Furthermore, patients coming with thyroid dysfunction must also be examined for liver abnormalities so that culprit cause of this thyroid abnormality could be treated from the root if present.