Efcacy and safety of combination therapy with bedaquiline in a multimorbid HIV positive patient with multiple drug resistant tuberculosis

Author:

Zhukova E. M.1,Kulchavenya E. V.2ORCID

Affiliation:

1. Novosibirsk Tuberculosis Research Institute

2. Novosibirsk Tuberculosis Research Institute; Novosibirsk State Medical University

Abstract

The article describes a clinical observation of the effective treatment of a multimorbid HIV positive patient with multiple drug resistant tuberculosis. It demonstrates modern approaches to treatment and optimal chemotherapy regimens containing bedaquiline. In the treatment of patients with a combination of chronic infectious diseases (tuberculosis, HIV infection, parenteral hepatitis) and oncological pathology (kidney cancer), interdepartmental interaction of specialists (phthisiologists, infectious disease specialists, and oncologists) is needed in order to compile successful treatment regimens taking into account multiple comorbidities and the risk of adverse reactions to drug combinations and choose the right time to perform a successful surgery.

Publisher

LLC "Medical Knowledge and Technologies"

Subject

General Medicine

Reference19 articles.

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4. Kaminskiy G.D., Kudlay D.A., Panova A.E., Parolina L.E., Peregudova A.B., Pshenichnaya N.Yu., Samoylova A.G., Testov V.V., Tinkova V.V. Taktika vracha pri vyyavlenii, diagnostike i profilaktike sochetannoy infektsii VICH i tuberkulez:prakticheskoe rukovodstvo. [Tactics of the physician in the detection, diagnosis and prevention of TB/HIV coinfection. Practical guide]. I.A. Vasilyeva, eds., Moscow, 2020, 152 p.

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1. Bedaquiline in the postoperative period of complex therapy of tuberculosis;Meditsinskiy sovet = Medical Council;2023-11-16

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