Affiliation:
1. Bashkir State Medical University
2. Pirogov Russian National Research Medical University
3. Republican Clinical Perinatal Center
Abstract
The objective: to evaluate the applicability of the nSOFA scale as a predictor of an unfavorable outcome in premature newborns.Subjects. The study was designed as retrospective and observational. The study enrolled 109 newborns with a gestational age of ≤ 32 weeks of pregnancy (birth weight 1,071 (772‒1,451) g, gestational age 29 (26‒32) weeks, 22 (20,4%) patients died. nSOFA scores were determined based on the first 72 hours after birth, and a peak values were used for analysis. Death was considered an unfavorable outcome.Results. The nSOFA score > 3 was associated with a odds ratio = 2.5 (CI 1.39–4.64, p = 0.002) for an unfavorable outcome. The area under the ROC curve was 0.796 (95% CI = 0.763–0.827).Conclusion. The nSOFA scale is an acceptable tool for measuring the severity of organ dysfunction and predicting mortality in premature newborns, regardless of the etiology of the disease.
Publisher
FSBEI HE I.P. Pavlov SPbSMU MOH Russia
Subject
Anesthesiology and Pain Medicine,Critical Care and Intensive Care Medicine,Emergency Medicine
Reference16 articles.
1. Aleksandrovich Yu.S., Gordeev V.I. Otsenochnye i prognosticheskie shkaly v meditsine kriticheskikh sostoyaniy. [Assessment and prognostic scales in critical medicine]. St. Peterburg, ELBI-SPb Publ., 2015, 320 p.
2. Vedeniye novorozhdenykh s respiratornym distress-syndromom recomend. Klinicheskiye rekomendatsii RASPM. [Managment of newborns with respiratory distress syndrome. Guidelines of Russian Association of Prenatal Medicine Specialists]. Acad. RAS N.N. Volodin, eds., Moscow, 2016, 48 p.
3. Mironov P.I., Lekmanov A.U. Evaluation of the validity of the nSOFA score in newborns with sepsis. Messenger of Anesthesiology and Resuscitation, 2021, vol. 18, no. 2, pp. 56-61. (In Russ.) doi.org/10.21292/2078-5658-2021-18-2-56-61.
4. Bonamy A.K.E., Zeitlin J., Piedvache A. et al. Wide variation in severe neonatal morbidity among very preterm infants in European regions. Arch. Dis. Child Fetal. Neonatal. Ed., 2018, vol. 104, pp. 36-45. doi: 10.1136/archdischild-2017-313697.
5. Flannery D.D., Edwards E.M., Puopolo K.M. et al. Early-onset sepsis among very preterm infants. Pediatrics, 2021, vol. 148, pp. e2021052456. doi: 10.1542/peds.2021-052456.
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