Effect of Routine Cytochrome P450 2D6 and 2C19 Genotyping on Antipsychotic Drug Persistence in Patients With Schizophrenia

Author:

Jürgens Gesche12,Andersen Stig E.12,Rasmussen Henrik B.3,Werge Thomas3,Jensen Heidi D.4,Kaas-Hansen Benjamin Skov1,Nordentoft Merete4

Affiliation:

1. Clinical Pharmacological Unit, Zealand University Hospital, Roskilde, Denmark

2. Department of Clinical Pharmacology, Bispebjerg and Frederiksberg University Hospitals, Copenhagen, Denmark

3. Mental Health Centre Sct Hans, Roskilde, Denmark

4. Copenhagen Research Center for Mental Health–CORE, Roskilde, Denmark

Publisher

American Medical Association (AMA)

Subject

General Medicine

Reference35 articles.

1. Utility and adoption of CYP2D6 and CYP2C19 genotyping and its translation into psychiatric clinical practice.;Jürgens;Acta Psychiatr Scand,2012

2. Cytochrome P450 testing for prescribing antipsychotics in adults with schizophrenia: systematic review and meta-analyses.;Fleeman;Pharmacogenomics J,2011

3. Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective cohort study.;Jukic;Lancet Psychiatry,2019

4. Does pharmacogenetic testing for CYP450 2D6 and 2C19 among patients with diagnoses within the schizophrenic spectrum reduce treatment costs?;Herbild;Basic Clin Pharmacol Toxicol,2013

5. Pharmacogenomic testing for psychotropic medication selection: a systematic review of the Assurex GeneSight Psychotropic Test.;Health Quality Ontario;Ont Health Technol Assess Ser,2017

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