Association of Impaired Cytochrome P450 2D6 Activity Genotype and Phenotype With Therapeutic Efficacy of Primaquine Treatment for Latent Plasmodium vivax Malaria

Author:

Baird J. Kevin12,Louisa Melva3,Noviyanti Rintis4,Ekawati Lenny2,Elyazar Iqbal2,Subekti Decy2,Chand Krisin2,Gayatri Anggi3,Instiaty 3,Soebianto Saraswati2,Crenna-Darusallam Chelzie4,Djoko Dwi5,Hasto Bambang Dwi5,Meriyenes Dubel5,Wesche David6,Nelwan Erni J.7,Sutanto Inge8,Sudoyo Herawati4,Setiabudy Rianto3

Affiliation:

1. Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

2. Eijkman-Oxford Clinical Research Unit, Eijkman Institute of Molecular Biology, Central Jakarta, Indonesia

3. Department of Pharmacology, Faculty of Medicine Universitas Indonesia, Jalan Salemba Raya No. 6, Central Jakarta, Indonesia

4. Eijkman Institute of Molecular Biology, Central Jakarta, Indonesia

5. Army Health Command, East Jakarta, Indonesia

6. Certara Strategic Consulting, Princeton, New Jersey

7. Division of Tropical Infectious Diseases, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Indonesia

8. Department of Parasitology, Faculty of Medicine, Universitas Indonesia, Central Jakarta, Indonesia

Publisher

American Medical Association (AMA)

Subject

General Medicine

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