Evaluation of the Cost-effectiveness of Drug Treatment for Alzheimer Disease in a Simulation Model That Includes Caregiver and Societal Factors

Author:

Ito Kouta12,Chapman Rick3,Pearson Steven D.3,Tafazzoli Ali4,Yaffe Kristine56,Gurwitz Jerry H.12

Affiliation:

1. Meyers Primary Care Institute, a joint endeavor of University of Massachusetts Medical School, Reliant Medical Group, and Fallon Health, Worcester

2. Division of Geriatric Medicine, University of Massachusetts Medical School, Worcester

3. Institute for Clinical and Economic Review, Boston, Massachusetts

4. Evidera, Bethesda, Maryland

5. Department of Psychiatry, Neurology, and Epidemiology and Biostatistics, University of California, San Francisco

6. San Francisco VA Medical Center, San Francisco, California

Publisher

American Medical Association (AMA)

Subject

General Medicine

Reference44 articles.

1. Alzheimer’s disease drug development pipeline: 2018.;Cummings;Alzheimers Dement (N Y),2018

2. Preclinical Alzheimer disease drug development: early considerations based on phase 3 clinical trials.;Hung;J Manag Care Spec Pharm,2020

3. Rapid drug access and scientific rigour: a delicate balance.;The Lancet Neurology;Lancet Neurol,2021

4. Assessing cost-effectiveness of early intervention in Alzheimer’s disease: an open-source modeling framework.;Green;Alzheimers Dement,2019

5. Preparing the health-care system to pay for new Alzheimer’s drugs.;Lin;Alzheimers Dement,2020

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